Title:

Maximal oxygen uptake is associated with the snp 13470 G>C polymorphism of the mitochondrial NADH dehydrogenase subunit 5 gene (mtND5) in caucasians from Poland

Creator:

Gronek, Piotr ; Holdys, Joanna ; Kryściak, Jakub ; Stanisławski, Daniel

Subject and Keywords:

mtND5 ; athletic performance ; endurance ; genetic polymorphism ; energy efficiency

Abstract:

Introduction. Physical performance displays a great inter-individual variance in both general population and among well-trained athletes. Genetic factor has an important contribution in this variance. The aim of this study was to examine the association between maximal oxygen uptake and genetic variants of mitochondrial NADH dehydrogenase subunit 5 gene (mtND5) in Caucasians from Poland. Material and Methods. The studies were carried out in a group of 154 men and 85 women, professional athletes representing various sports and fitness levels and students of the University of Physical Education in Poznań. Physiological and molecular procedures were used, i.e. direct measurement of maximal oxygen uptake (VO2max) and SNP 13470 G>C polymorphism of the mitochondrial NADH dehydrogenase subunit 5 gene (mtND5) was determined by restriction fragments length polymorphism (PCR-RFLP). Results. We have found that maximal oxygen uptake is associated with BamHI+/+ homoplasmic variant of the mtND5 gene in Caucasians from Poland. We have also observed positive influence of BamHI+ allele on level of maximal oxygen uptake (VO2max)

Publisher:

Akademia Wychowania Fizycznego w Poznaniu

Place of publication:

Poznań

Object type:

artykuły

ISBN/ISSN:

2299-9590

Language:

eng

Previous title:

Studies in Physical Culture and Tourism ; click here to follow the link

Is part of:

Trends in Sport Sciences 2013 Vol.20 No.4

Rights Management:

Akademia Wychowania Fizycznego w Poznaniu ; Biblioteka Akademii Wychowania Fizycznego w Poznaniu

Format:

pp.189-196

Publication date:

2013

Rights:

wszystkie prawa zastrzeżone

Access rights:

dla wszystkich w zakresie dozwolonego użytku

License:

udostępnianie na podstawie umowy z właścicielem majątkowych praw autorskich

Rights holder:

Akademia Wychowania Fizycznego w Poznaniu

Digitisation:

Biblioteka Akademii Wychowania Fizycznego w Poznaniu

Location of original object:

Biblioteka Akademii Wychowania Fizycznego w Poznaniu

Digital object format:

application/pdf